CREBBP Antibody

Size : 100 µL Clone Number: Aliases: CBP antibody; CBP_HUMAN antibody; CREB binding protein antibody; CREB-binding protein antibody; Crebbp antibody; Cyclic AMP responsive enhancer binding protein antibody; KAT3A antibody; RSTS antibody; RTS antibody; Rubinstein Taybi syndrome antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: Q92793 Immunogen: A synthesized peptide derived from Human CBP Host: Rabbit Reactivity: Human, Mouse, Rat Tested Applications: ELISA, WB, IHC, IF; WB: 1: 500-1: 2000, IHC: 1: 50-1: 200, IF: 1: 100-1: 500 Background: CBP a protein acetyltransferase that can transcriptionally activate histones. Acetylates the NCOA3 coactivator. Binds specifically to phosphorylated CREB1 and enhances its transcriptional activity toward cAMP-responsive genes. Methylation of the KIX domain by CARM1 blocks association with CREB, blocking CREB signaling, and activating the apoptotic response. Found in a complex containing NCOA2, NCOA3, IKKA, IKKB, and IKBKG. Probably part of a complex with HIF1A and EP300. Interacts with the C-terminal region of CITED4. The TAZ-type 1 domain interacts with HIF1A. Interacts with MAF, SRCAP, CARM1, ELF3, MLLT7/FOXO4, N4BP2, NCOA1, NCOA3, NCOA6, PCAF, PELP1, PML, SMAD1, SMAD2, SMAD3, SPIB and TRERF1. Interacts with HTLV-1 Tax, p30II, and HIV-1 Tat. Interacts with KLF1; Clonality: Polyclonal Isotype: IgG Purification Method: Antigen Affinity Purified Conjugate: Non-conjugated Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form: liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: CREBBP Research Areas: Epigenetics and Nuclear Signaling;Cancer;Metabolism?Microbiology;Stem cells