CDC42BPA Antibody

Size : 100 µL Clone Number: Aliases: A930014J19Rik antibody; CDC42 binding protein kinase alpha (DMPK like) antibody; CDC42 binding protein kinase alpha antibody; CDC42 binding protein kinase alpha dmpk like antibody; CDC42 binding protein kinase beta antibody; CDC42-binding protein kinase alpha antibody; CDC42BPA antibody; DKFZp686L1738 antibody; DKFZp686P1738 antibody; DMPK like antibody; DMPK-like alpha antibody; FLJ23347 antibody; KIAA0451 antibody; MGC189823 antibody; MRCK alpha antibody; mrck antibody; mrcka antibody; MRCKA_HUMAN antibody; Myotonic dystrophy kinase related CDC42 binding protein kinase alpha antibody; Myotonic dystrophy kinase-related CDC42-binding kinase alpha antibody; Myotonic dystrophy protein kinase-like alpha antibody; OTTHUMP00000035727 antibody; OTTHUMP00000035728 antibody; OTTHUMP00000035729 antibody; OTTHUMP00000035730 antibody; pk428 antibody; RP5-1087E8.4 antibody; Ser thr protein kinase PK428 antibody; Ser thr protein kinase related to the myotonic dystrophy protein kinase antibody; Serine/threonine protein kinase MRCK alpha antibody; Serine/threonine-protein kinase MRCK alpha antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: Q5VT25 Immunogen: Synthesized peptide derived from Internal of Human MRCKa. Host: Rabbit Reactivity: Human, Mouse, Rat Tested Applications: ELISA, WB, IHC, IF; WB: 1: 500-1: 3000, IHC: 1: 50-1: 200, IF: 1: 100-1: 200 Background: Serine/threonine-protein kinase which is an important downstream effector of CDC42 and plays a role in the regulation of cytoskeleton reorganization and cell migration. Regulates actin cytoskeletal reorganization via phosphorylation of PPP1R12C and MYL9/MLC2. In concert with MYO18A and LURAP1, is involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration. Phosphorylates: PPP1R12A, LIMK1 and LIMK2. May play a role in TFRC-mediated iron uptake. Wilkinson S., Nat. Cell Biol. 7: 255-261(2005). Totoki Y., Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases. Bechtel S., BMC Genomics 8: 399-399(2007). Clonality: Polyclonal Isotype: IgG Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Conjugate: Non-conjugated Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form: liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: CDC42BPA Research Areas: Signal transduction