Acetyl-H2AFZ (K4) Antibody

Size : 50 µL Clone Number: Aliases: H2A histone family member Z antibody; H2A.z antibody; H2A/z antibody; H2afz antibody; H2AZ antibody; H2AZ_HUMAN antibody; Histone H2A.Z antibody; MGC117173 antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: P0C0S5 Immunogen: Peptide sequence around site of Acetyl-Lys (4) derived from Human Histone H2A.Z Host: Rabbit Reactivity: Human Tested Applications: ELISA, WB, ICC, IF, IP, ChIP; Recommended dilution: WB: 1: 200-1: 2000, ICC: 1: 10-1: 100, IF: 1: 10-1: 100, IP: 1: 200-1: 2000 Background: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be required for chromosome segregation during cell division. Clonality: Polyclonal Isotype: IgG Purification Method: Antigen Affinity Purified Conjugate: Non-conjugated Buffer: Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: H2AFZ Research Areas: Epigenetics and Nuclear Signaling