DAPK2 Antibody

Size : 50 µg Clone Number: Aliases: DAK2 antibody; DAP kinase 2 antibody; DAP kinase related protein 1 antibody; DAP kinase related protein 1 beta isoform antibody; DAP-kinase-related protein 1 antibody; DAPK2 antibody; DAPK2_HUMAN antibody; Death associated protein kinase 2 antibody; Death-associated protein kinase 2 antibody; DRP 1 antibody; DRP-1 antibody; DRP1 antibody; MGC119312 antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: Q9UIK4 Immunogen: Recombinant Human Death-associated protein kinase 2 protein (222-370AA) Host: Rabbit Reactivity: Human, Mouse Tested Applications: ELISA, WB, IHC, IF; Recommended dilution: WB: 1: 500-1: 2000, IHC: 1: 20-1: 200, IF: 1: 50-1: 200 Background: Calcium/calmodulin-dependent serine/threonine kinase involved in multiple cellular signaling pathways that trigger cell survival, apoptosis, and autophagy. Regulates both type I apoptotic and type II autophagic cell deaths signal, depending on the cellular setting. The former is caspase-dependent, while the latter is caspase-independent and is characterized by the accumulation of autophagic vesicles. Acts as a mediator of anoikis and a suppressor of beta-catenin-dependent anchorage-independent growth of malignant epithelial cells. May play a role in granulocytic maturation. Isoform 2 is not regulated by calmodulin. It can phosphorylate MYL9. It can induce membrane blebbing and autophagic cell death. Clonality: Polyclonal Isotype: IgG Purification Method: 95%, Protein G purified Conjugate: Non-conjugated Buffer: Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: DAPK2 Research Areas: Cell biology