CTH Antibody, Biotin conjugated

Size : 50 µg Clone Number: Aliases: CGL_HUMAN antibody; CTH antibody; cystathionase (cystathionine gamma-lyase) antibody; Cystathionine gamma lyase antibody; Cystathionine gamma-lyase antibody; Cysteine desulfhydrase antibody; Gamma cystathionase antibody; Gamma-cystathionase antibody; Homoserine deaminase antibody; Homoserine dehydratase antibody; MGC9471 antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: P32929 Immunogen: Recombinant Human Cystathionine gamma-lyase protein (1-70AA) Host: Rabbit Reactivity: Human Tested Applications: ELISA Background: Catalyzes the last step in the trans-sulfuration pathway from methionine to cysteine. Has broad substrate specificity. Converts cystathionine to cysteine, ammonia and 2-oxobutanoate. Converts two cysteine molecules to lanthionine and hydrogen sulfide. Can also accept homocysteine as substrate. Specificity depends on the levels of the endogenous substrates. Generates the endogenous signaling molecule hydrogen sulfide (H2S), and so contributes to the regulation of blood pressure. Acts as a cysteine-protein sulfhydrase by mediating sulfhydration of target proteins: sulfhydration consists of converting -SH groups into -SSH on specific cysteine residues of target proteins such as GAPDH, PTPN1 and NF-kappa-B subunit RELA, thereby regulating their function. Clonality: Polyclonal Isotype: IgG Purification Method: 95%, Protein G purified Conjugate: Biotin Buffer: Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: CTH Research Areas: Cancer; Metabolism; Signal transduction