CLN5 Antibody, Biotin conjugated

Size : 50 µg Clone Number: Aliases: Ceroid lipofuscinosis neuronal 5 antibody; Ceroid-lipofuscinosis neuronal protein 5 antibody; CLN5 antibody; CLN5_HUMAN antibody; NCL antibody; Protein CLN5 antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: O75503 Immunogen: Recombinant Human Ceroid-lipofuscinosis neuronal protein 5 protein (42-181AA) Host: Rabbit Reactivity: Human Tested Applications: ELISA Background: Plays a role in influencing the retrograde trafficking of lysosomal sorting receptors SORT1 and IGF2R from the endosomes to the trans-Golgi network by controlling the recruitment of retromer complex to the endosomal membrane. Regulates the localization and activation of RAB7A which is required to recruit the retromer complex to the endosomal membrane (PubMed: 22431521). Clonality: Polyclonal Isotype: IgG Purification Method: 95%, Protein G purified Conjugate: Biotin Buffer: Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: CLN5 Research Areas: Neuroscience