CHM Antibody, Biotin conjugated

Size : 50 µg Clone Number: Aliases: dy; Chm antibody; Choroideraemia protein antibody; Choroideremia antibody; DXS540 antibody; FLJ38564 antibody; GGTA antibody; HSD 32 antibody; MGC102710 antibody; Rab escort protein 1 antibody; Rab geranylgeranyltransferase component A antibody; Rab proteins geranylgeranyltransferase component A 1 antibody; RAE1_HUMAN antibody; REP 1 antibody; REP-1 antibody; REP1 antibody; TCD antibody; TCD protein antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: P24386 Immunogen: Recombinant Human Rab proteins geranylgeranyltransferase component A 1 protein (1-653AA) Host: Rabbit Reactivity: Human Tested Applications: ELISA Background: Substrate-binding subunit of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B composed of RABGGTA and RABGGTB, and remains bound to it after the geranylgeranyl transfer reaction. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. Besides, a pre-formed complex consisting of CHM and the Rab GGTase dimer (RGGT or component B) can bind to and prenylate Rab proteins; this alternative pathway is proposed to be the predominant pathway for Rab protein geranylgeranylation. Clonality: Polyclonal Isotype: IgG Purification Method: 95%, Protein G purified Conjugate: Biotin Buffer: Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: CHM Research Areas: Neuroscience; Signal transduction