CFL2 Antibody

Size : 50 µL Clone Number: Aliases: CFL 2 antibody; CFL2 antibody; COF2_HUMAN antibody; Cofilin 2 muscle antibody; Cofilin antibody; Cofilin muscle antibody; Cofilin muscle isoform antibody; Cofilin-2 antibody; Cofilin2 antibody; muscle isoform antibody; NEM 7 antibody; NEM7 antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: Q9Y281 Immunogen: Recombinant Human Cofilin-2 protein (1-166AA) Host: Rabbit Reactivity: Human, Mouse Tested Applications: ELISA, WB, IHC; Recommended dilution: WB: 1: 1000-1: 5000, IHC: 1: 20-1: 200 Background: Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. Its F-actin depolymerization activity is regulated by association with CSPR3 (PubMed: 19752190). It has the ability to bind G- and F-actin in a 1: 1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods. Required for muscle maintenance. May play a role during the exchange of alpha-actin forms during the early postnatal remodeling of the sarcomere (By similarity). Clonality: Polyclonal Isotype: IgG Purification Method: Antigen Affinity Purified Conjugate: Non-conjugated Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: CFL2 Research Areas: Signal transduction