Cfb Antibody, Biotin conjugated

Size : 50 µg Clone Number: Aliases: Cfb antibody; Bf antibody; H2-BfComplement factor B antibody; EC 3.4.21.47 antibody; C3/C5 convertase) [Cleaved into: Complement factor B Ba fragment; Complement factor B Bb fragment] antibody Product Type: Polyclonal Antibody Immunogen Species: Mus musculus (Mouse) UniProt ID: P04186 Immunogen: Recombinant Mouse Complement factor B protein (23-761AA) Host: Rabbit Reactivity: Mouse Tested Applications: ELISA Background: Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B-lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes. Clonality: Polyclonal Isotype: IgG Purification Method: 95%, Protein G purified Conjugate: Biotin Buffer: Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: Cfb Research Areas: Immunology