CDH2 Antibody

Size : 50 µg Clone Number: Aliases: CADH2_HUMAN antibody; Cadherin 2 antibody; Cadherin 2 N cadherin neuronal antibody; Cadherin 2 type 1 antibody; Cadherin 2 type 1 N cadherin neuronal antibody; Cadherin 2; type 1; N-cadherin (neuronal) antibody; Cadherin-2 antibody; Cadherin2 antibody; Calcium dependent adhesion protein neuronal antibody; CD325 antibody; CD325 antigen antibody; CDH2 antibody; CDHN antibody; CDw325 antibody; CDw325 antigen antibody; N cadherin 1 antibody; N-cadherin antibody; NCAD antibody; Neural cadherin antibody; OTTHUMP00000066304 antibody; OTTHUMP00000067378 antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: P19022 Immunogen: Recombinant Human Cadherin-2 protein (746-906AA) Host: Rabbit Reactivity: Human, Mouse Tested Applications: ELISA, WB, IF; Recommended dilution: WB: 1: 2000-1: 10000, IF: 1: 50-1: 200 Background: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Acts as a regulator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adult subependymal zone: upon cleavage by MMP24, CDH2-mediated anchorage is affected, leading to modulate neural stem cell quiescence. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density (By similarity). Clonality: Polyclonal Isotype: IgG Purification Method: 95%, Protein G purified Conjugate: Non-conjugated Buffer: Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: CDH2 Research Areas: Cancer; Signal transduction; Stem cells