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CACNA1A Antibody

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Size : 50 µL Clone Number: Aliases: CACNA1A antibody; CACH4 antibody; CACN3 antibody; CACNL1A4 antibody; Voltage-dependent P/Q-type calcium channel subunit alpha-1A antibody; Brain calcium channel I antibody; BI antibody; Calcium channel antibody; L type antibody; alpha-1 polypeptide isoform 4 antibody; Voltage-gated calcium channel subunit alpha Cav2.1 antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: O00555 Immunogen: Recombinant Human Voltage-dependent P/Q-type calcium channel subunit alpha-1A protein (1838-2136AA) Host: Rabbit Reactivity: Human Tested Applications: ELISA, IHC, IF; Recommended dilution: IHC: 1: 20-1: 200, IF: 1: 50-1: 200 Background: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q-type calcium currents. P/Q-type calcium channels belong to the \'high-voltage activated\' (HVA) group and are blocked by the funnel toxin (Ftx) and by the omega-agatoxin-IVA (omega-Aga-IVA). They are however insensitive to dihydropyridines (DHP), and omega-conotoxin-GVIA (omega-CTx-GVIA). Clonality: Polyclonal Isotype: IgG Purification Method: Antigen Affinity Purified Conjugate: Non-conjugated Buffer: Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: CACNA1A Research Areas: Neuroscience; Cancer; Metabolism

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