C4BPB Antibody

Size : 50 µL Clone Number: Aliases: C4b binding protein beta chain antibody; C4b-binding protein beta chain antibody; C4BP antibody; C4BPB antibody; C4BPB_HUMAN antibody; Complement component 4 binding protein beta antibody; Complement component 4 binding protein beta chain antibody; Complement component 4-binding protein beta antibody; OTTHUMP00000034288 antibody; OTTHUMP00000034289 antibody; OTTHUMP00000034375 antibody; OTTHUMP0000003474 antibody; Proline rich protein antibody; PRP antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: P20851 Immunogen: Recombinant Human C4b-binding protein beta chain protein (18-252AA) Host: Rabbit Reactivity: Human, Mouse Tested Applications: ELISA, WB, IHC; Recommended dilution: WB: 1: 500-1: 5000, IHC: 1: 20-1: 200 Background: Controls the classical pathway of complement activation. It binds as a cofactor to C3b/C4b inactivator (C3bINA), which then hydrolyzes the complement fragment C4b. It also accelerates the degradation of the C4bC2a complex (C3 convertase) by dissociating the complement fragment C2a. It also interacts with anticoagulant protein S and with serum amyloid P component. The beta chain binds protein S. Clonality: Polyclonal Isotype: IgG Purification Method: Antigen Affinity Purified Conjugate: Non-conjugated Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: C4BPB Research Areas: Immunology