ALOX15B Antibody

Size : 50 µL Clone Number: Aliases: 15 Lipoxygenase 2 antibody; 15 LO 2 antibody; 15 LOX 2 antibody; 15-lipoxygenase 2 antibody; 15-LOX-2 antibody; 15-LOX-B antibody; Alox15b antibody; Arachidonate 15 lipoxygenase second type antibody; Arachidonate 15 lipoxygenase type II antibody; Arachidonate 15-lipoxygenase B antibody; Arachidonate 15-lipoxygenase type II antibody; LX15B_HUMAN antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: O15296 Immunogen: Recombinant Human Arachidonate 15-lipoxygenase B protein (1-200AA) Host: Rabbit Reactivity: Human Tested Applications: ELISA, IHC; Recommended dilution: IHC: 1: 20-1: 200 Background: Non-heme iron-containing dioxygenase that catalyzes the stereo-specific peroxidation of free and esterified polyunsaturated fatty acids generating a spectrum of bioactive lipid mediators. Converts arachidonic acid to 15S-hydroperoxyeicosatetraenoic acid/(15S)-HPETE. Also acts on linoleic acid to produce 13-hydroxyoctadecadienoic acid/13-HPODE. Has no detectable 8S-lipoxygenase activity but reacts with (8S)-HPETE to produce (8S,15S)-diHPETE. May regulate progression through the cell cycle and cell proliferation. May also regulate cytokine secretion by macrophages and therefore play a role in the immune response. May also regulate macrophage differentiation into proatherogenic foam cells. Clonality: Polyclonal Isotype: IgG Purification Method: Antigen Affinity Purified Conjugate: Non-conjugated Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: ALOX15B Research Areas: Cancer; Cardiovascular; Metabolism; Signal transduction