CD34 Monoclonal Antibody,PE Conjugated

Size : 50 Tests Clone Number: Aliases: Product Type: Monoclonal Antibody Immunogen Species: Human UniProt ID: P28906 Immunogen: Recombinant Protein Host: Mouse Reactivity: Human Tested Applications: ELISA,IF,FC;Recommended dilution: IF: 1: 100-1: 200 Background: D34 reacts with CD34 molecule, a 105-120 kDa heavily O-glycosylated transmembrane glycoprotein expressed on hematopoietic progenitor cells, vascular endothelium and some tissue fibroblasts. The intracellular chain of the CD34 antigen is a target for phosphorylation by activated protein kinase C suggesting that CD34 may play a role in signal transduction. CD34 may play a role in adhesion of specific antigens to endothelium. Clone 43A1 belongs to the class II epitope. * CD34 mAb is useful for detection and saparation of hematopoietic stem cells.1. Schlossman, SL et al., eds. (1995) Leucocyte Typing V : White Cell Differentiation Antigens, Oxford University Press, New York.2. Freeman SD et al., (1995) Blood 85: 20053. Thomas R and Lipsky PE. (1994) J Immunol 153: 40164. Nakamura Y. et al., (1994) Blood 83: 1442 Clonality: Monoclonal Isotype: IgG3 Purification Method: Affinity purified Conjugate: Non-conjugated Buffer: Phosphate-buffered solution, pH 7.4, containing 0.09% sodium azide and 0.2% (w/v) BSA Form: liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: CD34 Research Areas: Neuroscience?Cancer Cardiovascular;Developmental biology;Immunology;Stem cells