CTNNB1 Monoclonal Antibody

Size : 50 µL Clone Number: Aliases: Catenin beta-1 (Beta-catenin), CTNNB1, CTNNB Product Type: Monoclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: P35222 Immunogen: Synthesized peptide derived from human Beta-catenin Host: Mouse Reactivity: Human Tested Applications: ELISA, IHC; Recommended dilution: IHC: 1: 20-1: 200 Background: Involved in the regulation of cell adhesion. The majority of beta-catenin is localized to the cell membrane and is part of E-cadherin/catenin adhesion complexes which are proposed to couple cadherins to the actin cytoskeleton. Involved in signal transduction through the Wnt pathway. Nuclear beta-catenin it involved in transcriptional regulation by association with transcription factors of the TCF/LEF family. Clonality: Monoclonal Isotype: IgG2b, Kappa Purification Method: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. Conjugate: Non-conjugated Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: CTNNB1 Research Areas: Signal Transduction