CD4 Monoclonal Antibody,PE-Cy5 Conjugated

Size : 100 µL Clone Number: Aliases: Product Type: Monoclonal Antibody Immunogen Species: Human UniProt ID: P01730 Immunogen: Recombinant Protein Host: Mouse Reactivity: Human Tested Applications: ELISA,IF,FC;Recommended dilution: IF: 1: 100-1: 200 Background: CD4, also known as T4, is a 55 kD single chain transmembrane glycoprotein and belongs to immunoglobulin superfamily. CD4 is found on most thymocytes, a subset of T cells and at low level on monocytes/macrophages.CD4 is a co-receptor involved in immune response (co-receptor activity in binding to MHC class II molecules) and HIV infection (CD4 is primary receptor for HIV-1 surface glycoprotein gp120). CD4 regulates T-cell activation, T/B-cell adhesion, T-cell diferentiation, T-cell selection and signal transduction.1. Ledbetter, J et al. (1981) J Exp Med 153: 310-323.2. Haynes , B et al. (1986) Leukocyte Typing II: Human T lymphocytes. New York: Sprimger-Verlag; 3-30.3. Clevers H et al. (1988). Ann Rev Immunol 6 : 629-662.4. Barclay, N et al. (1993). The Leucocyte Factsbook. Academic Press. San Diego. Clonality: Monoclonal Isotype: IgG2b Purification Method: Affinity purified Conjugate: Non-conjugated Buffer: Phosphate-buffered solution, pH 7.4, containing 0.09% sodium azide and 0.2% (w/v) BSA Form: liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: CD4 Research Areas: Immunology;Stem cells