ADIPOQ Monoclonal Antibody

Size : 50 µg Clone Number: 1A1B3 Aliases: 30 kDa adipocyte complement-related protein Product Type: Monoclonal Antibody Immunogen Species: Human UniProt ID: Q15848 Immunogen: Recombinant Human Adiponectin Host: Mouse Reactivity: Human Tested Applications: ELISA Background: Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW. Clonality: Monoclonal Isotype: IgG2b Purification Method: 95%,Protein G purified Conjugate: Non-conjugated Buffer: Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form: liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: ADIPOQ Research Areas: Neuroscience?Cancer Cardiovascular;Metabolism;Signal transduction?Stem cells