CRP Monoclonal Antibody

Size : 50 µg Clone Number: 15E7B4 Aliases: CRP Product Type: Monoclonal Antibody Immunogen Species: Human UniProt ID: P02741 Immunogen: Recombinant Human CRP Protein Host: Mouse Reactivity: Human Tested Applications: ELISA,IHC;Recommended dilution: IHC: 1: 50-1: 500 Background: "C-reactive protein (CRP) is an annular (ring-shaped), pentameric protein found in blood plasma, the levels of which rise in response to inflammation (i.e., C-reactive protein is an acute-phase protein of hepatic origin that increases following interleukin-6 secretion from macrophages and T cells). Its physiological role is to bind to lysophosphatidylcholine expressed on the surface of dead or dying cells (and some types of bacteria) in order to activate the complement system via the C1Q complex. CRP is synthesized by the liver in response to factors released by macrophages and fat cells (adipocytes).It is a member of the pentraxin family of proteins.It is not related to C-peptide (insulin) or protein C (blood coagulation). C-reactive protein was the first pattern recognition receptor (PRR) to be identified." Clonality: Monoclonal Isotype: IgG Purification Method: 95%,Protein G purified Conjugate: Non-conjugated Buffer: Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form: liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: CRP Research Areas: Epigenetics and Nuclear Signaling;Cardiovascular;Immunology?Metabolism