CDH1 Monoclonal Antibody

Size : 50 µL Clone Number: 9H2D3 Aliases: Cadherin-1 (CAM 120/80) (Epithelial cadherin) (E-cadherin) (Uvomorulin) (CD antigen CD324) [Cleaved into: E-Cad/CTF1; E-Cad/CTF2; E-Cad/CTF3], CDH1, CDHE UVO Product Type: Monoclonal Antibody Immunogen Species: Human UniProt ID: P12830 Immunogen: Recombinant Human Cadherin-1 protein (155-707AA) Host: Mouse Reactivity: Human, Mouse Tested Applications: ELISA, WB, IF, FC; Recommended dilution: WB: 1: 500-1: 5000, IF: 1: 50-1: 200 Background: Cadherins are calcium-dependent cell adhesion proteins (PubMed: 11976333). They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells (PubMed: 11976333). Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7. Clonality: Monoclonal Isotype: IgG1 Purification Method: 95%, Protein G purified Conjugate: Non-conjugated Buffer: Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: CDH1 Research Areas: Cancer; Developmental biology; Signal transduction