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CD59 Monoclonal Antibody

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Size : 50 µg Clone Number: 2E11B6 Aliases: CD59 glycoprotein,HRF-20,MAC-IP,MACIF,MIRL,CD59 Product Type: Monoclonal Antibody Immunogen Species: Human UniProt ID: P13987 Immunogen: Recombinant CD59 Protein Host: Mouse Reactivity: Human Tested Applications: ELISA,WB,IHC;Recommended dilution: WB: 1: 500-1: 5000,IHC: 1: 50-1: 500 Background: CD59, also named as MIC11, MIN1, MIN2, MIN3, MSK21, MIRL, MACIF, HRF20 and 1F5 antigen, is a cell surface molecule glycoprotein with MW 18-25kd. It acts as a determinant of proximal–distal cell identity. CD59 acts by binding to the C8 and/or C9 complements of the assembling membrane attack complex (MAC), thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. It is involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase. Clonality: Monoclonal Isotype: IgG1 Purification Method: 95%,Protein G purified Conjugate: Non-conjugated Buffer: Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form: liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: CD59 Research Areas: Cardiovascular;Immunology;Signal transduction?Stem cells

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Internal Reference: CSB-MA0049471A0m

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